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Ardizzone A, Bova V, Casili G et al (2023) Role of basic fibroblast growth factor in cancer: biological activity, targeted therapies, and prognostic value

Results Safety All subjects completed the study

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Adjunct work if indicated: sleep specialist referral, additional biomarkers, or hormone evaluation when the clinical picture calls for it

As estrogen levels drop, there is a decrease in synaptic connections, a reduction in neurotrophic factor expression, and an overall weakening of the brains structural integrity, leading to memory difficulties and reduced cognitive performance [61]