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This revealed 38 variants that were both identified in our screen and characterized in the database as non-functional, damaging mutations (Fig

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These enzymes use glutathione to bind and neutralize toxic by-products, including reactive and oxidative compounds generated during alcohol metabolism

Consistent with previous research, our results show that GQD intervention significantly reduced IFN- and IL-17 secretion in colonic tissues, increased T cell numbers in the colonic mucosa, and decreased the proportions of IFN- + T cells and IL-17 + T cells

These differences are minor for GHK-CU and should not influence site selection significantly