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Activated amino acid response pathway generates apatinib resistance by reprograming glutamine metabolism in non-small-cell lung cancer

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The GlyNAC combination provides the most relevant evidence in the Kumar et al

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indicated that GPX4 and GSH levels were decreased, and cellular iron and MDA levels were increased in a mouse model of myocardial ischemiareperfusion (MIR, ischemia 30 min and reperfusion 24 h) injury [90]