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Human DP and epithelial cells were mixed with 2% v/v Matrigel-containing medium and seeded in 96-well spheroid formation plates

The organoselenium compound which has been most studied for its anti-inflammatory activity is diphenyl diselenide through its ability to modulate macrophage activation and inhibit the production of NO [3]

Tapkir et al

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These trials established specific efficacy rates, documented side effect profiles, and validated manufacturing processes down to the molecular level