The hero in this story
The small molecule inhibitors or gene silencing of GLS1 expression has shown antitumor activity in a variety of cancers, including melanoma (Varghese et al., 2021), breast cancer (Gross et al., 2014), pancreatic cancer (Son et al., 2013), acute myeloid leukemia (Emadi et al., 2014), and malignant glioma (Yamashita et al., 2021)
10.3748/wjg.v21.i17.5271 61 LiangS
Figure 3 Despite the clinical evidence for microbial infection in AD, other neurodegenerative diseases such as Parkinsons disease and ALS also are influenced by microbial infections and induction of inflammatory processes with microglial and astrocytic activation (Lotz et al., 2021), which would question the primacy of microbes in AD
Mack CM, Soares CJ, Wilson JK, Athanacio JR, Turek VF, Trevaskis JL, et al