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Yes, there are regulatory challenges, and the field is still evolving

Patient-centred strategies must identify patients tumour, current and planned conventional therapies (chemotherapy, endocrine therapy, targeted therapy and immunotherapy), comorbidities, organ function, nutrition profile, dietary habits and existing medication or supplement use since these factors critically impact both the efficacy and safety of supplementary approaches (236)

and Ahmed et al

You are undergoing chemotherapy or radiation (antioxidants can sometimes interfere with these treatments)

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