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Cells use glutathione to combat oxidative stress, a condition arising from an imbalance between antioxidants and free radicals in the body

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The generation of IP 3 results in release of endoplasmic reticulum (ER) stored Ca 2+ and the Ca 2+ , along with DAG, leads to activation of PKC

As expected, a 12-week course of HFD feeding induced early-stage liver pathologies of NAFLD in mice including fatty liver and liver injury, which were manifested by increased hepatic TG levels (Fig