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[9] A separate small multicenter Phase II trial (registered as NCT01393132) in patients with severe dry eye reported significant improvements in both signs and symptoms versus vehicle control

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In the United Kingdom, the Reference Nutrient Intake (RNI) for vitamin B12 is set at 1.5 micrograms (mcg) per day for adults aged 15 years and over, as established by the Department of Health's Committee on Medical Aspects of Food Policy (COMA)

Half of participants with obesity who received CagriSema reached a non-obese BMI by the end of treatment