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This important fatty acid seems to reduce the production of amyloid- proteins

organotypic hippocampal slice cultures that maintain an environment representative of an intact hippocampus were employed and evaluated for treatment-induced spinogenesis

Further studies revealed that treatment with N-acetylcysteine (NAC), a GSH precursor, significantly upregulates the GSH/GSSG ratio and increases the expression of GPX4, NRF2, and HO-1, effectively inhibiting ferroptosis (Zhang S

While it is not clear how this translates to the kinetics of cAMP production in cells expressing individual receptors, the divergence in peptide responses across each receptor is consistent with the dynamic conformational differences that were observed structurally for individual AMYRs bound to distinct peptides

DOI: Published online: April 16, 2024 1 Department of Internal Medicine, Bucheon St