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Hypoxia causes the production of ROS, which inhibit the degradation of the hypoxia-inducible factor 1 (HIF-1) (78)

How this is achieved in fungi capable of gliotoxin, BmGT and EGT biosynthesis (Sheridan et al., 2016), all of which are highly dependent on SAM utilization, and concomitant SAH generation ( Gliotoxin Biosynthesis De novo gliotoxin biosynthesis occurs as follows: Phenylalanine and serine are condensed by the non-ribosomal peptide synthetase GliP ( (1) (Figure 3)

Additional abundance files are included in Supplementary Data 2

Lipid Markers Determination by Electrospray Ionization High Resolution Mass Spectrometry (ESI-HRMS) Mouse liver was homogenized with a methanol:H 2 O (50:50) solution

Supplementary information Uncropped western blot membranes corresponding to Figs