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Human Molecular Genetics 17 , 20582069 (2008)

Specifically, vagal afferent neurons convey signals from the gut to the brain, whereas vagal efferent neurons transmit signals from the brain to the gut

A study by Eder et al

Patients with a history of severe cutaneous or other serious delayed-type reaction (e.g., drug reaction with eosinophilia and systemic symptoms or Stevens-Johnson syndrome) to an antimicrobial sulfonamide should be cautioned to maintain lifelong avoidance