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Increased concentrations of MDA have been detected in PD patients at both early and advanced stages (201.9 18.9 M/mg protein and 214.1 29.7 M/mg protein, respectively), significantly higher than in healthy controls (168.1 18.3 M/mg protein

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Finally, using online tools MetaboAnalyst 5.0 [40] and FELLA package (version 1.14) [41] to determine the differences in metabolite pathways of enrichment and analysis

In addition to boosting cognition, PE-22-28 shows potential for reducing neuroinflammation and oxidative stress, while also supporting mood regulation

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