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In vitro studies revealed that AOD9604 enhances the differentiation of adipose-derived mesenchymal stem cells into bone, stimulates the production of proteoglycans and collagen in chondrocytes, and promotes myoblast differentiation into muscle cells

Chronic stress Stress and anxiety can lead to a deficiency in glutathione

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Study limitations Oral NAC is associated with gastrointestinal discomfort, nausea, and diarrhea, but these symptoms are generally mild and occur at similar rates in placebo groups, indicating that NAC is well-tolerated and safe for chronic use [108]

However, the high recurrence rate after discontinuation suggests that simply suppressing systemic hormone levels may be insufficient to dismantle the established self-sustaining pathological network within the local microenvironment of the fibroids