Under homeostatic conditions, transient activation of NRF2 is cytoprotective, allowing for adaptation to various cell intrinsic (i.e., reactive oxygen species (ROS) generated by mitochondrial function) and extrinsic (i.e., xenobiotic) stressors (Kensler et al, 2007
Antibiotics and cell selection agents are used to select for specific cell populations to, for instance, generate a stable cell line or conduct a genetic
Shankar and Huberman reflect on how focus, reflection, sleep, and deliberate practice allow the brain to rewire well into adulthood
They were fasted overnight and then weighed
Several sources of ROS have been identified during diabetes, including enhanced blood glucose flux through the polyol and hexosamine pathway, increased formation of advanced glycation end products, and activation of protein kinase C pathway (137, 138)