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Another systematic review and comprehensive analysis indicated that antidepressants vary in their ability to enter amniotic fluid, cord blood, and breast milk, with citalopram having the highest permeability (mean permeability of active molecules: 2.03, range: 0.356.97) and fluoxetine having the lowest permeability (mean permeability of active molecules: 0.11, range: 0.020.20) (Figure 2)

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Highlighting the therapeutic implications of these findings, in utero antioxidant therapy stabilized RUNX2 and improved bone development in the Runx2+/ haplo-insufficient mouse model of human cleidocranial dysplasia

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