Long-term storage at -20C is recommended to maintain maximum purity
It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2
Strinic et al., "BPC 157 counteracts QTc prolongation induced by haloperidol, fluphenazine, clozapine, olanzapine, quetiapine, sulpiride, and metoclopramide in rats" [PubMed] K
This measured delivery allows consistent, controlled administration without oral digestion or invasive delivery methods
May your vials stay potent, your refrigerator stay cold, and your expiration dates stay far in the future.