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Its secreted hemolysins and exotoxins directly damage tissue and trigger inflammation 131

In conclusion, this evidence suggests ZnT2 serves as an innovative modulator for mucosal inflammation in colonic cells and plays a crucial role in coping with infectious colitis, opening up possibilities on manipulating ZnT2 as a novel treatment strategy to particular intestinal infections

Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias

Curr Opin Pharmacol 7:355359