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A 1997 single-blind randomized placebo-controlled trial by Khorram et al

These authors make the point that genetic effects often appear to be greater in males, perhaps related to their tendency to higher UA concentrations

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However, our data demonstrate a biphasic kinetic profile of dexamethasone-mediated ferroptosis modulation with protective effects upon longer exposure of renal epithelial cells to pro-ferroptotic stimuli