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These findings support the theory that high-fat diets (potentially causing insulin resistance and T2DM) hinder mitochondrial biogenesis, which could clarify the development of anomalous myocardial performance in cases of obesity, insulin resistance, and fully developed diabetes [153]

Limitations of Current Research No human trials: All existing data comes from animal studies or anecdotal self-experimentation

10.1093/eurjhf/hft132 23 JiaG.DeMarcoV

High doses can cause liver damage or worsen certain medical conditions