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The leading research compounds span four pathways: NAD+ (energy/sirtuin), Epithalon (telomere biology), MOTS-c (mitochondrial signaling), and GHK-Cu (gene expression/skin aging)

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During oxidative stress, the inability of Keap1 to bind NRF2 leads to NRF2 accumulation, which subsequently activates the expression of antioxidant genes