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Individuals with irritable bowel syndrome (IBS) exhibit elevated levels of bacteria related to intestinal inflammation, such as Enterobacteriaceae and Streptococcus , while the content of beneficial bacteria (such as Faecal Streptococcus ) decreases (Sciavilla et al., 2021)

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Moreover, the conversion of GGC to glutathione only requires 1 molecule of ATP as it is the product of the first step in glutathione synthesis, as shown in Figure 1