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Arch Gen Psychiatry 44 : 660669

The glutathione mechanism blocks tyrosinase, which is an enzyme that makes melanin

Rzepecki et al., 2019

Dendrobium candidum polysaccharides (DCPS) inhibited proliferation and induced apoptosis of human corneal epithelial cells (HCEC) under high glucose conditions, repairing HCEC damage [45]

Given the early stages of this therapeutic approach senescence therapeutics will need to overcome challenges related to biomarker identification, target engagement, CNS penetrance and safety