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Therefore, Cu(I) distribution is disturbed and might in turn enhance oxidative stress at copper-containing deposits or limit Cu, Zn-SOD1 activity in regions with decreased copper level

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Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder