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A cover letter that explained the study objectives was included at the beginning of the questionnaire, and the time for the completion of the questionnaire was about 510 min

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They include: Nicotine resinate, which is crucial for controlling the release of nicotine, alleviating withdrawal symptoms and reducing nicotine cravings Sorbitol, which acts as a sweetener Glycerol, which helps maintain the gums consistency These components contribute to the gums overall efficacy and user experience

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A 2019 review in Frontiers in Physiology concluded that chronic smoking is associated with endocrine disruption and may adversely affect hormone production, including testosterone