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(ii) ethanol 96% was given intragastrically in a dose of 1.0 ml/rat, as previously described (4-16, 30-33)

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This release of histamine and tryptase increases blood flow to the skeletal muscles during exercise.[ref] Hypoxia has also been shown to induce mast cell degranulation.[ref] This is a normal response for most people, and the body can handle a certain increase in histamine and tryptase