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With enhanced metabolism of HCC cells, competition for nutrients leads to increased FAO and decreased aerobic glycolysis, promoting ROS expression and inducing nuclear factor (Nrf2)-mediated M2 polarization (147, 148)

J Trace Elem Med Biol

The appropriate response to that uncertainty is not to abandon the compound but to use it within a structured clinical framework: defined goals, evidence-appropriate dosing, quality-assured sources, systematic monitoring, and ongoing reassessment as the science matures

Chilaka KN, Namoju R (2023) Maternal supplementation of alpha-lipoic acid ameliorates prenatal cytarabine-induced mutilation in reproductive development and function in F1 male adult rats

Plant immunity requires conformational charges of NPR1 via S-nitrosylation and thioredoxins