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Despite the lack of research on FMT from healthy donors to depressed recipients, the potential for FMT to be beneficial in treating MDD stems from the transmissibility of behaviors linked to microbiota (263, 264)

GIP receptors are present on immune cells, and GIP itself has demonstrated immunomodulatory properties in laboratory studies

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However, whether the change in risk perception caused by this levee effect is consistent across all groups or whether it varies due to heterogeneous individuals of the groups is worth further investigation