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We advise against use in patients with active cancer, cardiovascular disease, autoimmune disorders, liver or kidney disease, clotting issues, pregnancy or breastfeeding, or those under age 20

This guide presents a comprehensive MOTS-c dosage chart and week-by-week titration protocol, grounded in the published literature, to help clinicians and educated patients understand both the rationale for dosing decisions and the practical parameters of a safe, evidence-informed approach

If supplement-related

Clinics that follow sterile technique and have protocols for emergency response lower the overall risk of missing early systemic reactions

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