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EMT may generate cancer stem cells, leading to metastatic spread and resistance to therapy (Yang J

[PubMed] Chalasani N, Younossi Z, Lavine JE, Charlton M, Cusi K, Rinella M, Harrison SA, Brunt EM, Sanyal AJ (2018) The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

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That being said, the high doses of the nootropic measured at 0.5 mg/kg/day for intraperitoneal delivery and 2.0 mg/kg/day for oral delivery, and resulted in a performance that was indistinguishable from the control group and significantly better than the animals treated with scopolamine alone [2]