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Acknowledgments This work was supported by the National Natural Science Foundation of China (grant 81670336) and the Wenzhou Grant for Scientific Talents (RX2016003), Wenzhou Science and Technology Bureau
[148] found that the dipeptide l-alanyl-l-glutamine administration provided a beneficial ergogenic effect by increasing time to exhaustion following a mild hydration stress, and the effects were linked to an enhanced fluid and electrolyte absorption
Numerous complications may arise, such as rheumatoid vasculitis, permanent joint damage necessitating arthroplasty, and Felty syndrome, which may require splenectomy if left unattended (12, 58)
Taking the supplement with food, starting with a lower dose, may help alleviate such problems