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10.1086/340512 35 FalanyJ

The primary endpoint was the mean interval change in KI score from baseline to week 12

It functions in oxidative and alkylated genomic DNA base repair by identifying and cutting nucleotide chains at the 5apurinic (AP) site

In some cases, it may be through changes to the skin microbiome, but its not a guaranteed trigger

Compounds that serve as antioxidants, such as enzymes (e.g., Cu/Zn-superoxide dismutase [SOD], extracellular SOD, Mn-SOD, glutathione peroxidase, catalase) and low-molecular-weight antioxidants (e.g., uric acid and ascorbate), are induced early after ischemia and trauma