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A landmark randomized, double-blind, placebo-controlled trial published in Gut investigated the use of L-Glutamine in patients who developed diarrhea-predominant Irritable Bowel Syndrome (IBS-D) following an acute enteric infection

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This often leads to fatigue and dizziness among patients, making it challenging to stay active and continue treatment

As an extra control, also the plasma levels of a second metabolite indicative of reduced renal function, Creatinine, was measured

The injection can be given near the injury site for localized effects or in the abdomen for systemic applications like gut healing