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95 Similarly, in a unilateral ureteral obstruction (UUO)-induced CKD mouse model, elevated PKM2 induced the glycolytic pathway and lactate generation, which triggered histone Kla

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When starting over, review the reconstitution process carefully and ensure strict sterile technique throughout

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We previously showed that oral intake of long-term oscillating glucose (LOsG, 4 times/day for 38 days) can lead to -cells gaining metabolic memory in reactive oxygen species (ROS) stress, inhibition of insulin and SOD-2 expression, and the development of prediabetes with hypoinsulinemia and glucose intolerance [3]