Vinken M, Landesmann B, Goumenou M, Vinken S, Shah I, Jaeschke H, et al
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We found that, for SNP rs179982 (gene CPT2 ), patients with GG genotype had lower plasma L-Cn levels than those with AA genotype ( Figure 5A )
Consequently, the regulation of the expression of the membrane transporter SLC7A11, NADPH depletion because of glucose starvation, and subsequent disruption of the balance of thiol/disulfide bonds may serve as a common link between disulfidptosis and ferroptosis (Figure 2), potentially involving intersecting molecular pathways