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Severe Allergic Reaction (Anaphylaxis): Includes rash, severe itching, swelling of the face, throat, or tongue, or difficulty breathing

A steady, controlled stream over 15-30 seconds is ideal

The result is disproportionate loss of lean body mass with relative preservation of fat (or simultaneous fat loss in refractory cachexia)

Subtle cumulative changes often go unnoticed without visual reference