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Yes, in research settings, these two are sometimes studied together

Rigorous human studies are required to determine safety parameters, mechanistic specificity, and potential translational relevance before any clinical applications can be considered

However, despite the fact that these compounds have a long history of safe use, few clinical studies in pregnant women have been published

It is naturally present in human blood, saliva, urine, and its plasma concentration declines with age from approximately 200 ng/mL at age 20 to under 80 ng/mL after age 60

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