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[6] A second study by Ionescu and Frohman gave a single injection to healthy men and showed that GH secretion rose driven mostly by a marked increase in trough GH while preserving the normal pulsatile pattern, with a corresponding rise in IGF-1

Exp Neurobiol (2013) 22(1):117.10.5607/en.2013.22.1.11 10 LeeCSHanJHJangYYSongJHHanES

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For cells treated with ML226, a final concentration of 2.5 M was maintained throughout the assay to prevent washout

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