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The comparative advantage of this system is the redox activity (Ce 3+ /Ce 4+ ) of the cerium core, which acts as a regenerative antioxidant alongside the drug [59]

Schrama et al., 2022), in which authors used creatine or ethylenediamine tetra-acetic acid (EDTA) enriched fish diets to either reduce parvalbumin concentration or induce apo-parvalbumin (a free calcium binding ion structural form of parvalbumin with reduced IgE-binding capacity), respectively (Figure 2)

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Extensive persistent inflammation even when SARS-CoV-2-infected cells are only sporadically present at late stages of COVID-19 (Schurink et al., 2020) could also justify low GSH levels in association with over-abundance of cellular ROS, cellular oxidative damage, increased inflammation and cell death pathways activation seen in inflammaging (Zuo et al., 2019

Assessment of Colonic Damage The colonic segments (8 cm) were weighed, opened longitudinally and examined for damage