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Homozygous and compound heterozygous mutations, as well as dominantly inherited mutations in ABCC8 / KCNJ11 cause diffuse CHI, which is often unresponsive to first line diazoxide treatment and therefore suitable for therapy with second line somatostatin receptor ligands (SRLs)

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Examining the melting and boiling points for these halogens shows a trend that larger and heavier atoms display stronger IMFs, as shown by the higher melting and boiling points