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It is essential for protecting mycobacteria against a hostile environment such as anaerobic conditions, oxidative or nitrosative stress or the presence of antimicrobial compounds, and hence is critical in the development of resistance (Purwantini & Daniels, 1996

Concomitantly, systemic oxidative stress arising during liver damage can affect extrahepatic organs

Yes, glutathione is very sensitive to heat and oxygen

In parallel, we observed upregulation of canonical NRF2 target genes such as Gclc and Gclm , supporting the conclusion that melatonin augments NRF2 transcriptional activity in ILC2s

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