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Downstream effects commonly explored in experimental systems include modulation of IGF-1 signaling, protein synthesis pathways, lipid metabolism markers, and cellular repair processes

DOI: 10.1007/s10561-019-09797-0

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As shown in Table 1, the abundance of Lactobacillus, Desulfovibrio, Alistipes, Ruminococcus, and Lachnospiraceae decreased with EGCG intervention, whereas the abundance of Coprococcus, Prevotella, Bifidobacterium, Actinomyces, Adlercreutzia spp

To evaluate the PK properties, the GLP-1 albumin fusions were administered to human FcRn Tg32 mice by IV injections, and blood samples were collected for up to 12 days (Fig