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If tolerance is good and no adverse effects occur, increase to 75mg daily, often split into two doses of approximately 37.5mg each
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Also, in transgenic plants expressing the Ca 2+ -reporter aequorin, Glu, and cold could trigger an increase in [Ca 2+ ] cyt , and this increase was blocked by GLRs antagonists DNQX and CNQX (Meyerhoff et al., 2005)