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The alkylating chemotherapeutic temozolomide induces metabolic stress in IDH1-mutant cancers and potentiates NAD(+) depletion-mediated cytotoxicity

126 Endometrial cancer, one of the most prevalent malignancies of the female reproductive system, occurs mainly in perimenopausal and postmenopausal women

Arthritis Rheum 1977:1213-1216

An enlarged prostate can result in different uncomfortable urinary symptoms (such as increased nighttime voiding), as well as issues with the kidneys and bladder

In other embodiments, the formulations or compositions described herein are stable with respect to compound degradation over a period of at least about 1 week