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Advancing Phase II/III clinical trials targeting key nodes of ferroptosis (e.g., iron metabolism, GPX4 function, lipid peroxide clearance) is essential to confirm its therapeutic value and translational potential

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[DOI] [PubMed] [Google Scholar] 78.Agathos E., Tentolouris A., Eleftheriadou I., Katsaouni P., Nemtzas I., Petrou A., Papanikolaou C., Tentolouris N

doi:10.1016/S0022-3565(25)05394-7

H 2 S can improve diabetic renal injury through multiple mechanisms: alleviating high glucose-induced oxidative stress and activating the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant pathway