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Ipamorelin acts as an agonist at the ghrelin receptor (GHSR-1a) in the pituitary gland, stimulating the release of growth hormone through activation of specific signaling pathways (PMID: 9849822)

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Hence, astroglial cells are one of the primary targets for successful neuroprotective therapy as their alteration dramatically impact on neuronal survival and functionality

Tucotuzumab celmoleukin (EMD 273066 or huKS-IL2) is an immunocytokine consisting of tucotuzumab (anti-EpCAM antibody) and IL-2 (celmoleukin) [199]

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