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Established market leaders, R J Reynolds and American Tobacco, had over 60% of the US cigarette market between them

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The Tobacco Treatment Specialist (TTS) Training meets all of the requirements set forth in the Clinical Practice Guidelines for Treating Tobacco Use and Dependence as well as the national competencies for Tobacco Treatment Specialist acknowledged by The Association for Treatment of Tobacco Use and Dependence (ATTUD)

PMID 19105840

Thus, at steady state, bupropion hydrochloride extended-release (SR) tablets given twice daily, and the immediate-release formulation of bupropion given 3 times daily, are essentially bioequivalent for both bupropion and the 3 quantitatively important metabolites