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In contrast, during chronic or infected wound states, the pH shifts to alkaline levels (pH 79) as a result of microbial activity 53,54

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Supplement Support Certain supplements can ease histamine intolerance: DAO enzyme capsules taken before meals B12, folate, and B6 to strengthen methylation Probiotics carefully chosen for their effect on histaminesome strains reduce histamine, while others may increase it Lifestyle Habits That Help Daily habits can either calm or worsen symptoms: Stress raises histamine, so activities like meditation, yoga, or walking help