A time- and volume-controlled infusion pump was used to administer CGRP, and vital signs (i.e., blood pressure and heart rate) were recorded throughout the 1-hour in-hospital phase
Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)
Enter vial mg, water mL, target amount, and syringe type
Sulforaphane alone cannot directly stimulate autophagy at the 50 mg/kg dose associated with neuroprotection, but it could rescue rotenone-inhibited autophagy (Fig
Ann Internal Med 2019;171(9):633642