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doi: 10.3389/fphar.2023.1122632 Received 13 December 2022 Accepted 13 March 2023 Published 27 March 2023 Volume 14 - 2023 Edited by Enrico Sangiovanni, University of Milan, Italy Reviewed by Ayaz Shahid, Western University of Health Sciences, United States Andres A

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& Kamel, E.B

The multiple and complex actions of human GH were, however, acknowledged shortly after the advent of pituitary derived preparation of the hormone in the late fifties, as reviewed by Raben in 1962 (1)