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DEGs were identified using the DESeq2 R package, and results were visualized as a volcano plot using the ggplot2 R package ( Metabolic genes were defined based on a curated list 6,40

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These liposomes were then integrated into methacrylate hyaluronic acid hydrogel microspheres, which were capable of targeting chondrocytes and selectively remove subcellular dysfunction mitochondria

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